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Estrogen levels that are too high or even too low can cause the same symptoms of low testosterone: such as loss of sex drive, lethargy, and depression. Although this study does not prove that estrogen causes low testosterone in men, it is the first conclusive evidence that low testosterone is a side effect of hormone therapy. This could explain why women are more likely than men to experience these problems. In addition, because low testosterone in women affects their sexual desire, some women may become sexually frustrated when estrogen levels are too low or they are not able to build up enough testosterone to compensate for a low estrogen level. Low testosterone can also have other consequences such as decreased libido, hair loss, and prostate problems if estrogen levels are too low. In addition to low testosterone in men, estrogen is also believed to play a role in erectile dysfunction in men. It may also play a role in women, and possibly in both men and women. In summary In general, many men feel that their sexual health is affected by estrogen levels. It is common for both men and women to experience a "feel in the pants effect" due to an overabundance of estrogen in their bodies. For both men and women, estrogen can be treated with hormone therapy, as described below. Hormone therapy can lower a man's estrogen levels and lower the testosterone that men produce. Hormone therapy also lowers the level of the estrogen hormone called the "estrogen receptor" that is in the lining of the endocrine system that controls the production, function and distribution of both male and female hormones. This will prevent the overproduction of female hormones that can cause a woman's body to produce too much estrogen. It may also improve the functions of male hormones. (e.g., lowering risk of prostate cancer, increasing bone density and improving semen quality and quality of life) References Related Article: